Semaglutide for Weight Management: Mechanism and Protocol
GLP-1 receptor agonists like Semaglutide have transformed weight management research. Here's a deep dive into the mechanism, dosing, and what to expect.
Weight ManagementTirzepatide: The GIP/GLP-1 Dual Agonist Revolution
Tirzepatide (Mounjaro/Zepbound) is a once-weekly GIP/GLP-1 receptor agonist that produces sustained weight loss of 20-22% in clinical trials through dual appetite suppression and metabolic enhancement.
Weight ManagementRetatrutide: The Triple-Agonist Frontier in Weight Loss
Retatrutide is an investigational GIP/GLP-1/glucagon triple receptor agonist that achieved unprecedented 24% weight loss in phase 2 trials, representing the frontier of multi-receptor peptide therapy.
Weight ManagementAOD-9604: The GH Fragment for Selective Lipolysis
AOD-9604 is a synthetic fragment of human growth hormone (amino acids 176–191) that stimulates lipolysis via beta-3 adrenergic receptors without GH's anabolic or IGF-1 axis effects.